Choosing Prudent Solutions For Keratoconus
The corneal surface is normally smooth, so light can pass through with ease. Because of structural changes of shape and surface in keratoconus, the passing light is projected as a distorted image. First author of the study Sheldon J.J. Kwok said, Because light has the ability to probe deep inside tissue, were using that property to both go inside and change mechanical properties of tissue and to measure those changes so that we can understand how the tissue changed and visualize it noninvasively. Right now, ultraviolet light is used to perform crosslinking across the entire cornea. However, this comes with a risk of damaging the innermost layer of the cornea, a complication that changes the corneal function and can cause it to become very hazy. There is also no way to predict whether the procedure will actually improve vision in a given patient, added Seok-Hyun Yun, the research team lead. The researchers wanted to see if they could control the area of the crosslinking in the cornea using two-photon absorption. Generally, the two-photon absorption-based technique is used to harden liquid resins for various optical and 3D structures. The present research used this technique to stiffen the corneal tissue in a specific area. To test whether two-photon absorption could induce crosslinking, the scientists used a custom-made two-photon microscopy setup that delivers a specific kind of laser light through the objective lens.
For the original version including any supplementary images or video, visit http://www.belmarrahealth.com/keratoconus-corneal-disease-treatment-corneal-crosslinking-shows-promise-study/
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